Los Che are currently 13th in the table with seven points to show from their six matches, while Elche have also claimed seven points at this stage but have only played four times in the league this term.
Elche will certainly have been encouraged by their start to the season, with a record of two wins, one draw and one defeat from four matches representing an impressive opening for Jorge Almiron's side.
Los Franjiverdes started their campaign with a 3-0 defeat to Real Sociedad but put three points on the board four days later by recording an impressive 1-0 victory at Eibar.
Almiron's team then shared the points with Huesca before the international break before returning to winning ways last weekend with a 2-0 success at Alaves courtesy of goals from Pere Milla and Tete Morente.
Elche secured a return to Spain's top flight for the 2020-21 campaign by advancing through the Segunda Division playoffs last term, overcome Girona at the end of August.
The Green-striped ones last competed in La Liga in 2014-15, when they actually finished 13th but were relegated to the second tier because of unpaid debts to the tax authorities. A further relegation to the third tier of Spanish football for the 2017-18 campaign was an indication of their struggles at the time, but they are now back at the top level and will be determined to consolidate.
Valencia, meanwhile, have won two, drawn one and lost three of their six league matches to sit 13th in the table on seven points, just three points outside of the relegation zone.
Los Che made a fairly encouraging start to the campaign but have now lost their last two, suffering a 2-0 defeat to Real Betis on October 13 before being beaten 2-1 at Villarreal last weekend.
Head coach Javi Gracia recently revealed that he wants to leave the Mestalla and is only remaining in his position due to a contractual obligation, while key midfielder Geoffrey Kondogbia has hit out at the club's chairman Anil Murthy on social media, accusing the 47-year-old of 'destroying an ambitious project'.
The likes of Dani Parejo, Francis Coquelin, Ferran Torres, Rodrigo Moreno, Cristiano Piccini and Ezequiel Garay all moved on during the summer transfer window, while Garcia was unable to improve his team.
Valencia's squad is still full of talent, but it is very difficult to imagine them claiming a European spot this season, and the future of the club under owner Peter Lim is certainly unclear.
Elche La Liga form: LWDW
Valencia La Liga form: WLDWLL
There seems little reason for Almiron to change the side that impressively won at Alaves on Sunday, meaning that the goalscorers from that game, Milla and Morente, should continue in attack.
Guido Carrillo is one of the players pushing for a spot in the starting XI after featuring off the bench last time out, but the home side's head coach is unlikely to shuffle his pack here.
Kondogbia's involvement is the main talking point in terms of team selection for the visitors as the Frenchman was unable to take part against Villarreal due to a muscular injury.
Kondogbia's absence would see Carlos Soler line up in central midfield once again, but the latter could be moved wide if the former can prove his fitness in the build-up to kickoff on Friday night.
Elche possible starting lineup:
Badia; Barragan, Verdu, Calvo; Josan, Guti, Marcone, Fidel; Morente, Milla, Sanchez
Valencia possible starting lineup:
Domenech; Correia, Gabriel, Diakhaby, Gaya; Cheryshev, Wass, Soler, Guedes; Gameiro, Gomez
We say: Elche 1-1 Valencia
Valencia are in desperate need of a positive result, but it will not be a straightforward 90 minutes against Elche, who have impressed many with their performances early in the season. We are expecting a tight game at Estadio Manuel Martinez Valero on Friday night and fancy a low-scoring draw.