Birmingham City goalkeeper Jack Butland is back in the side, having sat out their FA Cup defeat to Leeds United during the week.
Lee Clark also brings in striker Robbie Hall and midfielder Callum Reilly to the starting lineup, while Stephen Carr is still out with a knee injury.
Gus Poyet has made two changes from Brighton & Hove Albion's 2-1 win over Derby County last weekend.
The Uruguayan boss has given the nod for forward Craig Mackail-Smith to start the match as well as bringing in keeper Thomas Kuzack.
Birmingham City: Butland; Caddis, Caldwell, Davies, Robinson; Burke, Gomis, Reilly, Elliott; Redmond, Hall.
Brighton & Hove Albion: Kuszczak, Calderon, Greer, El-Abd, Bridge; Bridcutt, Hammond, Orlandi; Lopez, Barnes, Mackail-Smith.
