Premier League leaders Tottenham Hotspur head to Crystal Palace for a London derby on Sunday afternoon.

Spurs have lost one of their last 20 games, a run that has seen them reach the last eight of the EFL Cup, last 32 of the Europa League and climb to the top of the Premier League.

Focus is now solely on retaining first place in the top flight ahead of next week's massive clash against reigning champions Liverpool.

Ahead of this weekend's trip to Selhurst Park, Sports Mole looks at how Tottenham could line up.

Out: Erik Lamela (foot)
Doubtful: Serge Aurier (knock)

> Click here for Tottenham's latest injury and suspension news ahead of this match

Sergio Reguilon and Giovani Lo Celso were Tottenham's only two survivors between the North London derby win over Arsenal and Europa League victory against Royal Antwerp.

Lo Celso was the best player on the pitch against Antwerp, but Mourinho will be cautious of starting him again this weekend, especially with plenty of other midfield options.

Harry Kane and Son Heung-min were brought on for the final 30 minutes in midweek, as was the previously doubtful Tanguy Ndombele, who missed the win against Arsenal.

In-form duo Kane and Son have combined for 11 Premier League goals this season - only Alan Shearer and Chris Sutton (13 in 1994-95), and Ryan Fraser and Callum Wilson (12 in 2018-19) have linked up for more in a single campaign.

In defence, Toby Alderweireld appears to be over a troublesome groin issue and should start alongside Eric Dier, with the well-rested Pierre-Emile Hojbjerg positioned just in front.

Video prediction

Watch the Sports Mole Football Shorts prediction for this game below: