The Catalan outfit's second team have struggled for form this season, with Saturday's 4-0 defeat at Real Zaragoza leaving them in 17th position in the Segunda.
Eusebio had been in charge of Barca B since 2011 but has now been removed, along with his assistant Pep Munoz.
Vinyals, who was in charge of the club's Juvenil A side, will oversee his first match at home to Deportivo Alaves on Saturday.
Restore Data
| Team | P | W | D | L | F | A | GD | PTS | |
| 1 | Real ValladolidValladolid | 41 | 21 | 9 | 11 | 50 | 34 | 16 | 72 |
| 2 | Leganes | 41 | 19 | 14 | 8 | 54 | 27 | 27 | 71 |
| 3 | EibarEibar | 41 | 20 | 8 | 13 | 68 | 45 | 23 | 68 |
| 4 | Espanyol | 41 | 16 | 18 | 7 | 56 | 40 | 16 | 66 |
| 5 | Real Oviedo | 41 | 17 | 13 | 11 | 52 | 35 | 17 | 64 |
| 6 | Racing de SantanderRacing | 41 | 18 | 10 | 13 | 63 | 54 | 9 | 64 |
| 7 | Sporting GijonSporting Gijon | 41 | 17 | 11 | 13 | 50 | 42 | 8 | 62 |
| 8 | ElcheElche | 41 | 16 | 11 | 14 | 43 | 44 | -1 | 59 |
| 9 | Racing Club de FerrolRacing de Ferrol | 41 | 15 | 14 | 12 | 49 | 51 | -2 | 59 |
| 10 | Levante | 41 | 13 | 19 | 9 | 49 | 45 | 4 | 58 |
| 11 | Burgos | 41 | 16 | 10 | 15 | 51 | 53 | -2 | 58 |
| 12 | TenerifeTenerife | 41 | 14 | 11 | 16 | 36 | 40 | -4 | 53 |
| 13 | CartagenaCartagena | 41 | 14 | 9 | 18 | 37 | 48 | -11 | 51 |
| 14 | Real ZaragozaZaragoza | 41 | 12 | 14 | 15 | 41 | 41 | 0 | 50 |
| 15 | Albacete | 41 | 12 | 14 | 15 | 49 | 55 | -6 | 50 |
| 16 | Eldense | 41 | 12 | 14 | 15 | 46 | 55 | -9 | 50 |
| 17 | Huesca | 41 | 11 | 15 | 15 | 36 | 33 | 3 | 48 |
| 18 | MirandesMirandes | 41 | 11 | 13 | 17 | 46 | 55 | -9 | 46 |
| 19 | Amorebieta | 41 | 11 | 12 | 18 | 37 | 52 | -15 | 45 |
| 20 | AlcorconAlcorcon | 41 | 10 | 13 | 18 | 31 | 52 | -21 | 43 |
| 21 | FC AndorraFC Andorra | 41 | 10 | 10 | 21 | 32 | 53 | -21 | 40 |
| 22 | Villarreal II | 41 | 10 | 10 | 21 | 40 | 62 | -22 | 40 |
| > Segunda Division Full Table | |||||||||
